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  Biomek® FX Laboratory Automation Workstation

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Biomek® FX Laboratory Automation Workstation

Biomek® FX Laboratory Automation Workstation

In today's environment, speed and performance are critical. You need technology that can be easily deployed and confidently adapted to multiple tasks by multiple researchers. That's why Beckman Coulter has designed a flexible liquid handling system that can simultaneously automate functionality of up to three liquid handlers all on the same worksurface. Offered either preconfigured in smart solutions for targeted applications or custom-tailored to meet your laboratory's individual needs, including the ADMETox Workstation for in vitro permeability analysis of ADME/Tox Assays using the high-throughput method, PAMPA. Because you only want what is best for you. Biomek FX. One Smart Solution!


Product Features

Automation Smart Solutions

Our Smart Solutions provide comprehensive systems that combine all the elements you need to employ and adapt the Biomek FX for specific applications. This includes task-specific hardware for rapid application configuration, easy to use software, chemistries with validated methods, and comprehensive global support. Putting it all together ensures reliable performance and enhanced productivity in your laboratory.

Biomek FX Dual Bridge System for Nucleic Acid Prep


Nucleic Acid Preparation Solution
  • Works with a variety of popular chemistries
  • Plasmid purification using vacuum filtration
  • Plasmid purification using magnetic beads
  • Integrated gripper can assemble / disassemble vacuum manifold for unattended operation
  • Software Wizard simplifies method creation
  • Fully automated 1-, 2- and 12-plate validated methods
  • Disposable barrier tips minimize cross-contamination
  • PCR* reaction setup and cleanup

Biomek FX Multichannel Pod With Integrated Gripper can Stack and Unstack vacuum Manifold


Biomek FX Single Bridge System with integrated Stacker Carousel for high capacity plate replication


Plate Replication Solutions
  • Four formatting options 96-96, 96-384, 384-96, 384-384
  • Add up to three reagents
  • Large plate capacity — up to 240 plates with Stacker Carousel
  • User interchangeable 96- or 384-channel pipetting heads
  • Software Wizard
  • Integrated gripper for moving labware
  • Automated tip loading

Biomek FX 384-Channel Head for pipetting into high density plates


Biomek FX integrated in SAGIAN Core System for high throughput screening


Screening Solutions
  • Biomek FX workstation easily integrates into SAGIAN™ Core System
  • Primary and secondary screening configurations
  • Multichannel pipetting for rapid compound transfers and reagent addition
  • Eight-channel independent axis pipetting for adding controls and performing dilutions
  • Powerful SAMI® Software for easy method creation and optimizing scheduler

ORCA® Robot loading a plate into detector


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Biomek FX modularity adapts to a wide variety of applications


Flexible Automation
  • The Biomek FX Laboratory Workstation is the most flexible automated liquid handling systems available today. A large worksurface accommodates most any job size. The system comes configured with one or two pipetting capabilities for unsurpassed versatility on a single system.
  • Automated Labware Positioners (ALPs) allow the researcher to customize the worksurface with automated functionality such as shaking, stirring, heating and cooling to for a given application.
  • The Biomek FX software is unparalleled for ease-of-use and power. Rich with features for precise and accurate pipetting, as well as automation tools makes it simple to write methods to automate any task.
  • Our application-specific Software Wizards take ease-of-use to a new level by dialoging with the researcher about the task and then automatically generating validated methods.

Biomek FX Multichannel Pod accepts both 96- or 384-Channel Disposable Tip Pipetting Heads


Biomek FX 96- or 384-Channel Disposable Tip Pipetting Heads

Biomek FX Span-8 Pipettor with independent well, vial or tube access


Biomek FX Span-8 Pipettor

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Biomek FX Main Software Screen


Software
  • The power of simple selectivity is what makes Biomek FX software so invaluable. Palettes and feature-rich method Wizards put quick method creation at your fingertips. And customized editing is just a click away. Advanced features support other complex operations and data handling/information management needs. Because for today's liquid handling demands, Biomek FX's high-speed, high-capacity selectivity is not only ingenious...it's indespensable.

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Biomek FX Plate Replication Software Wizard

  • Step Palettes for drag-n-drop method creation
  • Liquid types, pipetting techniques and templates
  • Labware and deck editors
  • Online help, method validation and estimate run times
  • Worklist, variables loops, and run method
  • Application-specific method Wizards
  • DS-8772B: Biomek® FX System Software (PDF Format)

Biomek FX Linear Shaking ALP


ALPs
  • The Biomek FX has a large flexible worksurface. Integral to the system are Automated Labware Positioners (ALPs) that are uniquely designed to fit seamlessly onto the deck. These ALPs perform application-specific tasks and make it simple to configure the system for a wide variety of applications. ALPs, one more reason the Biomek FX is the smart solution for your liquid handling needs.
  • Automated Tip Loader ALP
  • Linear Shaking ALP
  • Magnetic Stirring ALP
  • Heating and Cooling ALP

Biomek FX Magnetic Stirring ALP



Applications
  • Plate Replication
  • Primary Screening
  • Secondary Screening
  • Plasmid Purification using vacuum filtration
  • Plasmid Purification using magnetic beads
  • PCR* Reaction Setup
  • PCR* Reaction Cleanup
  • Sequencing Reaction Setup
  • Dye Terminator Removal
  • Genomic DNA purification from blood

More Info
Click to enlarge image
ADMETox Workstation. ADME toxicity assays for in vitro permeability measurements, automating the PAMPA method for the determination of passive absorption.

ADMETox Workstation. ADME toxicity assays for in vitro permeability measurements, automating the PAMPA method and Caco-2 assays.


ADMETox Workstation

Early drug discovery ADME toxicity assays, such as fast Caco-2 screens, can help in rejecting test compounds that lack good pharmaceutical profiles. A cost-effective high-throughput method, PAMPA (Parallel Artificial Membrane Permeability Analysis), which uses a phospholipid artificial membrane that models passive transport of epithelial cells, is becoming increasingly popular. The pION PAMPA Evolution 96 System (with Double-Sink and Gut-Box*) is a new surrogate assay that predicts the gastrointestinal-tract absorption of candidate drug molecules at different pH conditions.

The Biomek FXP Single-Bridge Laboratory Automation Workstation PAMPA Assay System features a 30-minute incubation time using an on-deck integrated Gut-Box and SpectraMax* (Molecular Devices) microplate spectrophotometer. The permeability coefficients of drug standards with diverse physiochemical properties were compared from both PAMPA and Caco-2 assays automated using the Biomek FX Workstation. These automated assays can be used for high-throughput ADME toxicity screening in early drug discovery.

Additional ADMETox Workstation information:

* All trademarks are the property of their respective owners. Where applicable, the PCR process is covered by patents owned by Roche Molecular Systems, Inc., and F. Hoffmann-LaRoche, Ltd.

For Research Use Only; not for use in diagnostic procedures.

Additional Information:


 

 
 
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