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Native-condition protein characterization. For better lead optimization.
An important component of lead optimization is the ability to evaluate a drug candidate under concentrated "shelf-life" conditions before it moves into expensive preclinical or clinical trials. The ProteomeLab XL-A/XL-I functions over a wide range of concentration, temperature, ionic strength and pH, delivering more thorough characterization than other methods.
Our unique operating methodology measures the relative change in the distribution of molecular weights, providing an efficient way to measure heterogeneity, stoichiometry and self-associating systems.
Because the ProteomeLab XL-A/XL-I's measurements are based on the first principles of thermodynamics and hydrodynamics, no standards or calibrations are required. As a result, you spend less time on setup, and more time on discovery.
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