| ProteomeLab™ IgY-R7
Rodent-Optimized Proteome Partitioning Kits target seven highly abundant
proteins: Albumin, IgG, Transferrin, Fibrinogen, IgM, α1-Antitrypsin and
Haptoglobin
The ProteomeLab IgY-R7 Proteome Partitioning kits are specifically
designed to remove seven highly abundant proteins from rodent biological
fluids such as serum and plasma. This provides an enriched pool of lower
abundant proteins, free from interference by the abundant proteins,
ready for discovery and validation of biomarkers, drug targets, and
therapeutic proteins and antibodies.
Kits are available in both spin column and LC column formats,
depending upon the desired capacity per cycle. The observed capacity of
mouse or rat serum or plasma varies from 10 µL to 200 µL depending on
the species and kit selected (see below). Our IgY (avian) based
technology uses physiological buffers for binding and washing, and
avoids urea and other chaotropic agents for elution that can precipitate
at low temperature.
Our ProteomeLab IgY-R7 spin column kit is specifically designed to work
in combination with the ProteomeLab SP Sample Preparation system, while
the higher capacity LC kits are designed to work with the ProteomeLab
PPS Sample Preparation system.
The lower abundant proteins in the flow-through fraction and the
highly abundant proteins in the bound/eluted fractions can be further
fractionated with the ProteomeLab PF 2D system, advancing the detection
and identification of low abundant proteins.
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Albumin
IgG
Transferrin
Fibrinogen
IgM
α1-Antitrypsin
IgM
Haptoglobin
The ProteomeLab IgY-R7 Proteome
Partitioning kits target these
seven highly abundant proteins.
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